Original Article

Liver Injury, Autoimmune, and Cholestatic Diseases

Bile Drainage Improves Survival in Amatoxin-induced Severe Liver Injury: A Prospective Pilot Cohort Study Xiuying Ma, Bin Han, Wei Yue, Yuan Shen, Jiawei Geng Published online: April 27, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2026.00057

Hepatic and Biliary Neoplasia

Metabolic Dysfunction-associated Steatotic Liver Disease Diminishes the Efficacy of miR-125b-5p-engineered MSC Therapy for Hepatocellular Carcinoma via HK2 Upregulation: A Multimodal Theranostic Study Lishan Shen, Xiaowen Luo, Xiaorui Su, Xiang Zhou, Fengyun Zou, Shuangshuang Zhong, Yayin Deng, Boya Yin, Zhicheng Yao, Ruomi Guo Published online: May 11, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00709

Liver Failure, Cirrhosis and Portal Hypertension

Consensus versus Outcome-based Definitions of Acute-on-chronic Liver Failure: Implications for Risk Stratification and Case Identification Nipun Verma, Tingting Qi, Pratibha Garg, Arun Valsan, Gowripriya Nair, Julian Pohl, Arathi Venu, Xianbo Wang, Xin Zheng, Guohong Deng, Yan Huang, Zhongji Meng, Yanhang Gao, Zhiping Qian, Xiaobo Lu, Feng Liu, Yu Shi, Jia Shang, Yubao Zheng, Yingli He, Meiqian Hu, Changze Hong, Sina Jameie-Oskooei, Raj Mookerjee, Mohammad Mahdi Saeidinejad, Sunil Taneja, Jinjun Chen, Hai Li, Ajay Duseja, Cornelius Engelmann, Rajiv Jalan Published online: May 15, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2026.00267

A Novel Simplified Prognostic Model for 90-day Transplant-free Survival in Patients with Severe Acute Liver Injury/Acute Liver Failure Yan Ren, Manman Xu, Wenling Wang, Ming Kong, Yu Chen Published online: April 28, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2026.00075

Review Article

The Association of Alpha-1 Antitrypsin Deficiency and Arterial Aneurysms: An Update and Review Moana Da Silva Santiago, George Y. Wu Published online: April 27, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2026.00043

The Multifaceted Roles of Gut Microbiota and Their Metabolites in Metabolic Dysfunction-associated Steatotic Liver Disease: A Literature Review Yunqi Zhang, Dengqin Wang, Bo Zhuang, Fangzhuo Zhu, Chengwei Tan, Jing Zhang, Qianqian Zhang Published online: April 24, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00605

Dubin-Johnson and Rotor Syndromes: A Review and Update of Pathophysiological Mechanisms Bianca Thakkar, George Y. Wu Published online: April 9, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00560

Mechanisms and Prognostic Assessment Value of Thyroid Hormone in Liver Failure Hong Zhou, Hong Wu, Shao-Hui Su, Shan-Hong Tang Published online: March 18, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00657

Illuminating and Instructive Clinical Case

Occlusion of Paraspinal Vein Shunt Alleviated Post-TIPS Hepatic Myelopathy in a Patient with Cirrhosis Yuhong Suo, Lixue Xu, Xinyan Zhao, Yu Wang, Fuliang He, Jidong Jia Published online: May 14, 2026 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2026.00044