Improved Discrimination and Predictive Ability of Novel Prognostic Scores for Long-term Mortality in Hospitalized Patients with Cirrhosis

Sipu Wang, Gaoyue Guo, Han Wang, Xuqian Zhang, Wanting Yang, Jie Yang, Liping Wu, Chao Sun

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00004

Investigation of HO-1 Regulation of Liver Fibrosis Related to Nonalcoholic Fatty Liver Disease Through the SIRT1/TGF-ß/Smad3 Pathway

Mengjiao Sun, Xiaoqing Wu, Zhandong Lin, Congyue Zhang, Jiawei Cui, Yaoyao Mao, Yue Shi, Jiaming Zhang, Yuemin Nan

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00481

Intestinal Depletion of TM6SF2 Exacerbates High-fat Diet-induced Metabolic Dysfunction-associated Steatotic Liver Disease through the Gut-liver Axis

Li-Zhen Chen, Yu-Rong Wang, Zhen-Zhen Zhao, Shou-Lin Zhao, Cong-Cong Min, Yong-Ning Xin

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00407

Ketamine Hepatotoxicity: An Underappreciated Cause of Liver Damage - Analysis by RUCAM

Bianca Thakkar, George Y. Wu

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00478

Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies

Tongtong Li, Xuan Shen, Tao Zhang, Jiaheng Ren, Wang Wang, Didi Wang, Pengxia Zhang

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00369

Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis

Xiaoyuan Xu, Yujuan Guan, Jinghang Xu, Song Yang, Yifan Han, Jidong Jia, Yuemin Nan, Lai Wei, Zhongping Duan, Hui Zhuang, Liver Fibrosis, Cirrhosis and Portal Hypertension Group, Chinese Society of Hepatology, Chinese Medical Association

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00105

Molecular and Histological Profiles and Relevant Imaging Signatures of Intrahepatic Cholangiocarcinoma

Huizhen Huang, Feng Chen

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00410

The Role of Novel Immunomodulators in the Treatment of Autoimmune Hepatitis

Jing Li, Huanhuan Wang, Jie Lin, Aili Wang, Shuiyin Miao, Huaie Liu

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00008

Corrigendum: Liver Characterization of a Cohort of Alpha-1 Antitrypsin Deficiency Patients with and without Lung Disease

Published online: June 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00201C

Adrenomedullin as an Immunomodulator of CD14⁺MerTK⁺ Circulating Monocytes in Liver Failure Syndromes

Francesca Maria Trovato, Florent Artru, Roosey Sheth, Rima Abdalla, Joseph Wilson, Anna Broderick, John Smith, Stephen Atkinson, Mark J. McPhail

Published online: June 24, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00074

Assessment of Metabolic Dysfunction-associated Steatotic Liver Disease and Liver Fibrosis: A Cross-sectional Study in Asymptomatic Individuals in Greater Vancouver

Nicholas W. Tjandra, David M.P. Di Fonzo, Tianyi Wen, Kirby Lau, Peter Kwan, Eric M. Yoshida, Daljeet Chahal

Published online: June 23, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00109

Orphan Nuclear Receptors in Metabolic Dysfunction-associated Steatotic Liver Disease Development

Huan Li, Jian Chen, Ziyin Huang, Mingkai Chen

Published online: June 19, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00019

Complete Resolution of Refractory Ascites and Pleural Effusion with Sustained Improvement in Urinary Sodium Excretion in a Cirrhotic Patient Treated with Empagliflozin

Wei Qin, Yunyi Gao, Yuanyuan Zhao, Ning Bian, Weiguang Fan, Wei Wang, Yuan Gao, Zhongjie Hu

Published online: June 19, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00172

Short-term Physical Activity Reduces Metabolic-associated Steatohepatitis by Promoting the Degradation of Branched-chain Amino Acids in Skeletal Muscle

Mingshu Gao, Jiaying Li, Yanan Zhang, Jiangtao Huang, Jiaqi Chen, Dawen Liao, Shengnan He, Qian Bi, Lele Ji, Yulu Du

Published online: May 30, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00072

Global Trends and Cross-country Inequalities of Acute Hepatitis E in the Elderly, 1990–2021: A Comprehensive Analysis

Deliang Huang, Jinyan Jiang, Jinghan Peng, Zhibin Zhu, Yuanyuan Chen, Siyu Zhang, Huiyi Lai, Hong Yu, Qi Zhao, Yanna Wu, Yanping Chen, Jun Chen

Published online: May 30, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00101

Corrigendum: Ursolic Acid Modulates Estrogen Conversion to Relieve Inflammation in Metabolic Dysfunction-associated Steatotic Liver Disease via HSD17B14

Published online: May 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00414C

Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Hepatitis B: Protocol for a Phase 3 Randomized Trial

Xiaobo Cai, Yin Qu, Wen Xie, Yanbin Wang, Mengyu Zhao, Ling Zhang, Ying Luo, Ping Yin, Jun Cheng, Lungen Lu

Published online: May 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00472

Analysis of the Disease Spectrum Characteristics of Inherited Metabolic Liver Diseases in Two Hepatology Specialist Hospitals in Beijing over the Past 20 Years

Wei Hou, Yuanzhi Huang, Tang Shang, Zheng Wang, Wei Zhang, Kefi Wang, Yinjie Gao, Min Zhang, Sujun Zheng

Published online: May 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00030

GTF3C2 Promotes the Proliferation of Hepatocellular Carcinoma Cells through the USP21/MEK2/ERK1/2 Pathway

Yani Wu, Yingnan Yang, Youju Zhang, Qiuran Xu, Dongsheng Huang, Kangsheng Tu

Published online: May 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00386

FTO Promotes Hepatocellular Carcinoma Progression by Mediating m6A Modification of BUB1 and Targeting TGF-βR1 to Activate the TGF-β Signaling Pathway

Lin Zhang, Li Gan, Yuru Lin, Zhechuan Mei, Shengtao Liao

Published online: May 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00007